
Thermo Fisher Scientific CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (BCMA/2366)
Human CD269/BCMA 단백질을 인식하는 mouse monoclonal antibody로, IHC, ELISA, Peptide Array 등 다양한 연구용 분석에 적합함. Recombinant human BCMA(aa 1-184)를 immunogen으로 사용하며, preservative-free PBS buffer에 1 mg/mL 농도로 제공됨.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCMA/2366 |
| Immunogen | Recombinant human CD269 protein fragment (around aa 1–184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes and may be important for B cell development and autoimmune response. It specifically binds to TNFSF13B/TALL-1/BAFF, leading to NF-kappaB and MAPK8/JNK activation. It also interacts with TRAF family members, transducing signals for cell survival and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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