Thermo Fisher Scientific TRAF2 Recombinant Rabbit Monoclonal Antibody (3S2A8)
TRAF2 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot, ELISA, IP 등에 사용 가능. 인간, 생쥐, 랫트 시료에 반응하며, 높은 특이성과 재현성을 제공. HEK293 세포에서 발현된 IgG 형식의 액상 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:25,000–1:100,000 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3S2A8 |
| Immunogen | Recombinant fusion protein containing amino acids 190–350 of human TRAF2 (NP_066961.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093784 |
Product Specific Information
Immunogen sequence:
DGCGKKKIPR EKFQDHVKTC GKCRVPCRFH AIGCLETVEG EKQQEHEVQW LREHLAMLLS SVLEAKPLLG DQSHAGSELL QRCESLEKKT ATFENIVCVL NREVERVAMT AEACSRQHRL DQDKIEALSS KVQQLERSIG LKDLAMADLE QKVLEMEAST Y
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) act as adaptor proteins linking TNF receptor superfamily members to intracellular signaling pathways. They regulate cell death and stress responses by mediating receptor-proximal signaling events. TRAF2 and TRAF3 bind to CD40, a receptor critical for NF-κB activation in B lymphocytes. TRAF2 also participates in CD40 signaling in non-hematopoietic cells and interacts with lymphotoxin-beta receptor (LTβR) along with TRAF3, cIAP1, and Smac to regulate apoptosis and immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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