Thermo Fisher Scientific NeuN Recombinant Rabbit Monoclonal Antibody (2F9F0)
NeuN 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2F9F0 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human NeuN (A6NFN3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3092424 |
Product Specific Information
Immunogen sequence:
MAQPYPPAQY PPPPQNGIPA EYAPPPPHPT QDYSGQTPVP TEHGMTLYTP AQTHPEQPGS EASTQPIAGT QTVPQTDEAA QTDSQPLHPS DPTEKQQPKR
Target Information
Fox-3 (also known as NeuN, HRNBP3, RBFOX3 or Fox-1 homolog C) is a 350 amino acid protein containing one RRM (RNA recognition motif) domain. It is localized to both the nucleus and cytoplasm and is suggested to regulate alternative splicing events.
Fox-3 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes more than 1,200 genes.
Chromosome 17 includes two key tumor suppressor genes, p53 and BRCA1:
- p53 maintains genetic integrity by regulating DNA repair and cell death.
- BRCA1 is involved in DNA repair and is linked to early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland, and fallopian tubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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