Thermo Fisher Scientific CDK6 Recombinant Rabbit Monoclonal Antibody (8G3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:5,000

-

Immunoprecipitation (IP)

1:200-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8G3

Immunogen

A synthesized peptide derived from human CDK6 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDK6,uniProtId:Q00534-1,ncbiNodeId:9606,antigenRange:311-326,antigenLength:326,antigenImageFileName:MA5-38360_CDK6_Q00534-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38360_CDK6_Q00534-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2898274

Product Specific Information

This antibody has been tested in direct-ELISA

Target Information

CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.