Thermo Fisher Scientific GluR4 Polyclonal Antibody, Biotin

Applications

• Western Blot (WB): 0.3–1 µg/mL

Product Specifications

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA and kainate/AMPA receptors, both containing glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven subunits (GluR1–7). These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, while NMDA receptors are characterized by slower kinetics and high Ca²⁺ permeability.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.