Thermo Fisher Scientific DUOX1 Polyclonal Antibody
DUOX1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체입니다. IHC(P)에서 4-6 µg/mL로 사용 가능하며, 인간 시료에 반응합니다. 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence EKFQRSCLHQTVQ |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933016 |
Product Specific Information
- Expected to recognize both reported isoforms (NP_059130.2; NP_787954.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
- Preliminary analysis showed no signal in Western Blot.
Target Information
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide-generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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