Thermo Fisher Scientific SCP2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.3 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 3–6 µg/mL

Product Specifications

Product Specific Information

This antibody is expected to recognize isoform 1, 2, 6, 7, and 8 (NP_002970.2; NP_001007099.1; NP_001180529.1; NP_001180528.1; NP_001180546.1 respectively).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
The transcript from the proximal promoter encodes SCPx, while the distal promoter encodes SCP2; both share a common C-terminus.
SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, and SCP2 is an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, characterized by peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.