Thermo Fisher Scientific ANGPT1 Monoclonal Antibody (OTI8H2), TrueMAB
인간 ANGPT1 단백질을 인식하는 단클론 항체로, Western blot과 IHC(P)에서 검증됨. E.coli에서 생산된 재조합 단백질(aa 198-498)을 면역원으로 사용. Lyophilized 형태로 제공되며, PBS(pH 7.3)과 trehalose 함유. 혈관 발달 및 안정성 연구용에 적합한 연구 전용 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 198–498 of human ANGPT1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Angiopoietins are key regulators of vascular development and angiogenesis.
They bind to an endothelial cell-specific tyrosine-protein kinase receptor, activating it through tyrosine phosphorylation.
The ANGPT1 protein plays a crucial role in interactions between the endothelium and surrounding matrix, contributing to blood vessel maturation and stability, and may be involved in early heart development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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