Thermo Fisher Scientific AGT Monoclonal Antibody (OTI10D2), TrueMAB
AGT 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 유래 AGT 재조합 단백질(aa 34-331)을 면역원으로 제작되었습니다. 동결건조 형태로 제공되며, PBS 기반 버퍼에 trehalose 포함. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 34–331 of human AGT produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The AGT gene encodes pre-angiotensinogen, a precursor expressed in the liver. It is cleaved by renin into angiotensin I, which is further processed by ACE to form angiotensin II, a key regulator of blood pressure.
Mutations in AGT are linked to essential hypertension, renal tubular dysgenesis, atrial fibrillation, and inflammatory bowel disease.
This antibody is intended for Research Use Only, not for diagnostic or resale purposes.
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