Thermo Fisher Scientific TCF12 Monoclonal Antibody (2E9)
TCF12 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(2E9). Western blot, IHC, ELISA에 적합하며, 인간 시료에서 반응. PBS buffer, 무보존제, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E9 |
| Immunogen | TCF12 (NP_996919, 364–453 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
VGSPSPLTGT SQWPRPGGQA PSSPSYENSL HSLKNRVEQQ LHEHLQDAMS FLKDVCEQSR MEDRLDRLDD AIHVLRNHAV GPSTSLPAGH
Target Information
TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG.
It is expressed in various tissues including skeletal muscle, thymus, B- and T-cells, and participates in regulating lineage-specific gene expression through heterodimer formation with other bHLH E-proteins.
TCF12, together with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation.
Recent studies indicate that TCF12 is essential for the development of invariant natural killer T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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