Thermo Fisher Scientific Actin alpha 1, Skeletal Muscle Monoclonal Antibody (ACTA1/360)
사람 유래 ACTA1 단백질을 인식하는 단클론 항체로, 골격근 알파 액틴 검출에 적합합니다. Western blot, IHC, ICC, Flow Cytometry 등 다양한 응용에 사용 가능하며, 단백질 A/G 정제 및 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACTA1/360 |
| Immunogen | Recombinant human ACTA1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to show a broad reactivity.
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play essential roles in cell motility, structure, and integrity. Alpha, beta, and gamma actin isoforms have been identified — alpha actins are major constituents of the contractile apparatus, while beta and gamma actins regulate cell motility. This actin is an alpha actin found in skeletal muscle. Mutations in this gene are associated with several congenital myopathies, including nemaline myopathy type 3, congenital myopathy with excess thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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