Thermo Fisher Scientific RING1 Monoclonal Antibody (OTI6F11), TrueMAB
RING1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western Blot에 최적화됨. 인간, 마우스, 랫트 반응성. 무보존제, 동결건조 형태로 제공. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 88–362 of human RING1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The RING1 gene encodes a protein belonging to the RING finger family, characterized by a zinc-binding motif related to the zinc finger domain.
This protein can bind DNA and act as a transcriptional repressor. It is associated with the polycomb group protein complex and interacts with BMI1, EDR1, and CBX4, colocalizing in large nuclear domains.
It interacts with CBX4 via its glycine-rich C-terminal domain and maps to the HLA class II region, contiguous with RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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