Thermo Fisher Scientific Zika Virus NS1 Monoclonal Antibody (EA23)
Zika Virus NS1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, ELISA 및 면역세포화학(ICC/IF)에 사용 가능. 높은 특이성과 재현성을 제공하며, 다른 Flavivirus와 교차반응 없음. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:10–1:50
ELISA
- Tested Dilution: 1:20–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EA23 |
| Immunogen | Recombinant Zika Virus NS1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633554 |
Product Specific Information
MA5-24582 does not cross-react with the following viruses:
Dengue 1–4, TBE virus, West Nile virus, Yellow Fever virus, Japanese Encephalitis virus, and Chikungunya virus.
Target Information
Zika virus (ZIKV), a member of the Flaviviridae family, possesses a single positive-sense RNA genome that is translated as a polyprotein and subsequently cleaved into structural (C, PrM/M, E) and nonstructural (NS1–NS5) proteins.
The glycosylated NS1 forms a homodimer within cells, essential for viral replication, and later assembles into a hexameric lipoprotein particle secreted extracellularly. This particle aids immune evasion and pathogenesis by interacting with both innate and adaptive immune components.
References:
1) Song, H.; Qi, J.; Haywood, J.; Shi, Y.; Gao, G.F. (2016). Nat. Struct. Mol. Biol. 23, 456–458.
2) Suthar, M.S.; Diamond, M.S.; Gale, M. Jr. (2013). Nat. Rev. Microbiol. 11, 115–128.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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