Thermo Fisher Scientific RDH12 Monoclonal Antibody (1E11)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

Immunocytochemistry (ICC/IF)

Assay-Dependent

-

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

1E11

Immunogen

RDH12 (NP_689656.1, 217 a.a. ~ 316 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RDH12,uniProtId:Q96NR8-1,ncbiNodeId:9606,antigenRange:217-316,antigenLength:316,antigenImageFileName:MA5-24524_RDH12_Q96NR8-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24524_RDH12_Q96NR8-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2633496

Product Specific Information

Peptide Sequence: RLQGTGVTTY AVHPGVVRSE LVRHSSLLCL LWRLFSPFVK TAREGAQTSL HCALAEGLEP LSGKYFSDCK RTWVSPRARN NKTAERLWNV SCELLGIRWE

Target Information

The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.