Thermo Fisher Scientific EZH2 Recombinant Rabbit Monoclonal Antibody (10H8)
EZH2 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, IHC(P) 및 ELISA에 사용 가능. 높은 특이성과 재현성을 제공하며, 인간 시료에 반응. 액상 형태로 제공되며 -20°C 이하에서 안정적으로 보관 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10H8 |
| Immunogen | A synthesized peptide derived from human KMT6/EZH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092729 |
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes that maintain the transcriptional repressive state of genes over successive cell generations.
This protein interacts with embryonic ectoderm development protein, VAV1 oncoprotein, and X-linked nuclear protein.
EZH2 may play roles in hematopoietic and central nervous systems. Mutations in EZH2 are associated with Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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