Thermo Fisher Scientific CD357/GITR Monoclonal Antibody (GITR/1585)
인간 GITR 단백질을 인식하는 마우스 단클론 항체로 ELISA에 적합. 비표지(Unconjugated) 형태이며, Protein A/G로 정제됨. PBS 완충용액(0.05% BSA, 0.05% sodium azide) 내 액상 보관. 4°C에서 보관하며 동결 금지.
- 카탈로그번호
- 8784-MSM3-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD357/GITR Monoclonal Antibody (GITR/1585)
Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GITR/1585 |
| Immunogen | Human full-length TNFRSF18 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is a protein encoded by the TNFRSF18 gene in humans. It is mapped to 1p36.33 and encodes a member of the TNF-receptor superfamily. The receptor shows increased expression upon T-cell activation and is thought to play a key role in maintaining dominant immunological self-tolerance by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice suggest its involvement in regulating CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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