Thermo Fisher Scientific Human Caspase 5 Synthetic Peptide
인간 Caspase-5의 아미노 말단 16개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 차단용 블로킹 펩타이드로 사용 가능. 고순도 정제된 액상 형태이며 PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0228
- 판매단위
- pk
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Thermo Fisher Scientific Human Caspase 5 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human Caspase-5.
PEP-0228 can be used as a blocking peptide with polyclonal antibody PA5-20110.
Target Information
Caspases are a family of cysteine proteases divided into apoptotic and inflammatory subfamilies.
Unlike apoptotic caspases, inflammatory caspases are associated with immune responses to microbial pathogens.
Members include caspase-1, -4, -5, and -12. Activation of these caspases leads to cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18.
Caspase-5 interacts with caspase-1; both are constituents of the NALP1 inflammasome, which triggers cleavage of pro-IL-1β.
Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-γ.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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