Thermo Fisher Scientific Human Caspase 4 Synthetic Peptide
Human Caspase-4의 중심부 15개 아미노산 서열로 구성된 합성 펩타이드. PA5-20109 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS buffer(pH 7.2, 0.1% BSA 포함)에 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP0227
- 카테고리
- Nitriles
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human Caspase 4 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human caspase-4.
PEP-0227 can be used as a blocking peptide with polyclonal antibody PA5-20109.
Target Information
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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