
Thermo Fisher Scientific NEUROG1 Monoclonal Antibody (OTI5H10), TrueMAB
NEUROG1 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC, IP에 적합합니다. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 제품입니다. 신경세포 분화 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2–4 µg/mg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5H10 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human NEUROG1 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neurogenin 1 (NEUROG1) is a basic helix-loop-helix (bHLH) transcription factor involved in determining neuronal cell fate during development. It plays dual roles in cell-fate specification—promoting neurogenesis while inhibiting astrocyte differentiation. NeuroG1 activates neuronal gene expression and suppresses astrocyte differentiation by sequestering the CREB-binding protein transcription complex and inhibiting STAT transcription factors required for gliogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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