Thermo Fisher Scientific PAM Polyclonal Antibody
Rabbit 유래의 Polyclonal 항체로 Human, Mouse, Rat 시료에서 MYCBP2 단백질 검출에 적합. Western blot에 1:500~1:2,000 희석 비율로 사용 가능. 액상 형태, 1 mg/mL 농도, PBS+50% glycerol 보존. 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYCBP2 (Accession O75592), corresponding to amino acid residues S979–E1029 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900241 |
Product Specific Information
Antibody detects endogenous levels of total MYCBP2.
Target Information
This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients, and a mutation in this gene has been identified in patients with a rare inherited vision defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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