Thermo Fisher Scientific MECOM Polyclonal Antibody
MECOM 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot 및 Immunocytochemistry에 사용 가능하며, 인간 시료에 반응합니다. PBS와 50% glycerol에 보관되며, -20°C에서 안정적으로 저장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MECOM (Accession Q03112), corresponding to amino acid residues I100–Y150. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900242 |
Product Specific Information
Antibody detects endogenous levels of total Myelodysplasia Syndrome 1.
Target Information
EVI1 (MECOM) is a transcriptional regulator and oncoprotein involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation. It interacts with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9.
The EVI1 gene can undergo translocation with the AML1 gene, resulting in overexpression of EVI1 and the onset of leukemia. Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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