Thermo Fisher Scientific OSTM1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Concentration: 1 µg/mL

Product Specifications

Product Specific Information

Positive test controls include:

• HeLa
• 293T
• A-549
• Raji
• B cells
• Mouse brain
• Mouse kidney

Target localization: Lysosome membrane, Single-pass type I membrane protein

Immunogen sequence:
ALPFGSSPHR VFHDLLSEQQ LLEVEDLSLS LLQGGGLGPL SLPPDLPDLD PECRELLLDF ANSSAELTGC LVRSARPVRL CQTCYPLFQQ VVSKMDNISR AAGNTSESQS CARSLLMADR MQIVVILSEF FNTTWQEANC ANCLTNNSEE LSNSTVYFLN LFNHTLTCFE HNLQGNAHSL LQTKNYSEVC KNCREAYKTL SSLYSEMQKM NELENKAEPG THLCIDVEDA MNITRKLWSR TFNCSVPCSD TVP

Target Information

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway.
The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region.
This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity.
It is highly conserved from flies to humans.
Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.