Thermo Fisher Scientific OSTM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 32-284 of human OSTM1 (NP_054747.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OSTM1,uniProtId:Q86WC4-1,ncbiNodeId:9606,antigenRange:32-284,antigenLength:334,antigenImageFileName:PA5-120130_OSTM1_Q86WC4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120130_OSTM1_Q86WC4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.79 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913702

Product Specific Information

Positive test controls include: HeLa, 293T, A-549, Raji, B cells, Mouse brain, Mouse kidney. The target is usually found in the following locations: Lysosome membrane, Single-pass type I membrane protein.

Immunogen sequence: ALPFGSSPHR VFHDLLSEQQ LLEVEDLSLS LLQGGGLGPL SLPPDLPDLD PECRELLLDF ANSSAELTGC LVRSARPVRL CQTCYPLFQQ VVSKMDNISR AAGNTSESQS CARSLLMADR MQIVVILSEF FNTTWQEANC ANCLTNNSEE LSNSTVYFLN LFNHTLTCFE HNLQGNAHSL LQTKNYSEVC KNCREAYKTL SSLYSEMQKM NELENKAEPG THLCIDVEDA MNITRKLWSR TFNCSVPCSD TVP

Target Information

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.