Thermo Fisher Scientific LPIN3 Monoclonal Antibody (OTI1C8), TrueMAB
LPIN3 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합합니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS 완충액(8% 트레할로스) 내 보존, -20℃에서 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Full length human recombinant protein of human LPIN3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Human lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice with mutations in the fatty liver dystrophy gene show similar phenotypes. The Lpin1 gene was identified as responsible for fatty liver dystrophy in mice, encoding the nuclear protein lipin.
Lipin is essential for normal adipose tissue development and may serve as a candidate gene for human lipodystrophy.
Human homologs include LPIN1 (2p25), LPIN2 (18p11), and LPIN3 (20q11–q12). The corresponding mouse genes Lpin1, Lpin2, and Lpin3 are mapped to chromosomes 12, 17, and 2, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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