Thermo Fisher Scientific CAPN5 Monoclonal Antibody (OTI8F10), TrueMAB
인간 CAPN5 단백질(aa 274-578)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 적합하며, 무보존제 동결건조 형태로 제공. 재구성 후 1 mg/mL 농도 유지 가능. 신호전달 및 세포 과정 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 274–578 of human CAPN5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Calpains are calcium-dependent cysteine proteases that participate in signal transduction and other cellular processes.
A functional calpain protein consists of an invariant small subunit and one of a family of large subunits. CAPN5 is one such large subunit.
Unlike some calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Due to its similarity to the Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also referred to as HTRA3.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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