Thermo Fisher Scientific SFRS2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SFRS2 (AAH66958, 1 a.a. approximately 179 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SRSF2,uniProtId:Q01130-1,ncbiNodeId:9606,antigenRange:1-221,antigenLength:221,antigenImageFileName:H00006427-B01P_SRSF2_Q01130-1_House_mouse.svg,antigenImageFileNamePDP:H00006427-B01P_SRSF2_Q01130-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MSYGRPPPDV EGMTSLKVDN LTYRTSPDTL RRVFEKYGRV GDVYIPRDRY TKESRGFAFV RFHDKRDAED AMDAMDGADP GVGAVPGLAA DLATAARSLG PALVLDLGRP PSPDPHEGPS PSPRRSPDLV RGPGPGLGPG VLPQCPRGNP NPGRDRRVPP SLLKRKERCP LKKMLRSPV

Target Information

The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35. In addition, a pseudogene of SC35 has been found on chromosome 11.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.