Thermo Fisher Scientific SFTPB Monoclonal Antibody (1H7)
Thermo Fisher Scientific의 SFTPB 단클론 항체(1H7)는 인간 SFTPB 단백질을 인식하는 Mouse IgG2a 항체입니다. Western Blot과 ELISA에 사용 가능하며, 친화 크로마토그래피로 정제되었습니다. PBS(pH 7.4) 용액에 보존되며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H7 |
| Immunogen | SFTPB (NP_000533.2, 1 a.a. ~ 381 a.a.) full-length recombinant protein with GST tag. MW of GST tag: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MAESHLLQWL LLLLPTLCGP GTAAWTTSSL ACAQGPEFWC QSLEQALQCR ALGHCLQEVW GHVGADDLCQ ECEDIVHILN KMAKEAIFQD TMRKFLEQEC NVLPLKLLMP QCNQVLDDYF PLVIDYFQNQ TDSNGICMHL GLCKSRQPEP EQEPGMSDPL PKPLRDPLPD PLLDKLVLPV LPGALQARPG PHTQDLSEQQ FPIPLPYCWL CRALIKRIQA MIPKGALAVA VAQVCRVVPL VAGGICQCLA ERYSVILLDT LLGRMLPQLV CRLVLRCSMD DSAGPRSPTG EWLPRDSECH LCMSVTTQAG NSSEQAIPQA MLQACVGSWL DREKCKQFVE QHTPQLLTLV PRGWDAHTTC QALGVCGTMS SPLQCIHSPD L
Target Information
Pulmonary surfactant is a complex mixture of phospholipids and proteins secreted from type II alveolar cells. It reduces surface tension at the alveolar air-liquid interface, ensuring alveolar stability for normal ventilation. Four distinct surfactant proteins are identified: SP-A, SP-B, SP-C, and SP-D.
- SP-A (28–36 kDa) and SP-D (43 kDa): collagenous carbohydrate-binding proteins
- SP-B (8–9 kDa) and SP-C (4 kDa): non-collagenous hydrophobic proteins
SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns, but not in squamous cell or large cell carcinomas of the lung or nonpulmonary adenocarcinomas. ProSP-B is glycosylated in the Golgi apparatus and undergoes proteolytic processing by a cathepsin D-like protease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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