Thermo Fisher Scientific SFTPB Monoclonal Antibody (2H6)
Thermo Fisher Scientific의 SFTPB 단클론항체(2H6)는 인간 SFTPB 단백질을 특이적으로 인식하는 Mouse IgG2a 항체입니다. Western blot과 ELISA에 적합하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H6 |
| Immunogen | SFTPB (NP_000533.2, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MAESHLLQWL LLLLPTLCGP GTAAWTTSSL ACAQGPEFWC QSLEQALQCR ALGHCLQEVW GHVGADDLCQ ECEDIVHILN KMAKEAIFQD TMRKFLEQEC NVLPLKLLMP QCNQVLDDYF PLVIDYFQNQ TDSNGICMHL GLCKSRQPEP EQEPGMSDPL PKPLRDPLPD PLLDKLVLPV LPGALQARPG PHTQDLSEQQ FPIPLPYCWL CRALIKRIQA MIPKGALAVA VAQVCRVVPL VAGGICQCLA ERYSVILLDT LLGRMLPQLV CRLVLRCSMD DSAGPRSPTG EWLPRDSECH LCMSVTTQAG NSSEQAIPQA MLQACVGSWL DREKCKQFVE QHTPQLLTLV PRGWDAHTTC QALGVCGTMS SPLQCIHSPD L
Target Information
Pulmonary surfactant is a complex mixture of phospholipids and proteins secreted from type II alveolar cells. It reduces surface tension at the air-liquid interface, ensuring alveolar stability for normal ventilation. Four surfactant proteins (SP-A, SP-B, SP-C, SP-D) have distinct properties:
- SP-A (28–36 kDa) and SP-D (43 kDa) are collagenous carbohydrate-binding proteins.
- SP-B (8–9 kDa) and SP-C (4 kDa) are non-collagenous hydrophobic proteins.
SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns, but not in squamous cell or large cell carcinomas, nor in nonpulmonary adenocarcinomas. ProSP-B is glycosylated in the Golgi apparatus and undergoes proteolytic processing by a cathepsin D-like protease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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