Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI2H6), TrueMAB

Applications and Tested Dilution

• Application: Western Blot (WB)
• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex, which consists of elongins A/A2, B, and C.
This complex enhances RNA polymerase II elongation by reducing transient pausing during transcription.
Elongin A acts as the active transcriptional component, while elongins B and C serve regulatory roles.
Elongin A2 is testis-specific and forms a stable complex with elongins B and C.
The von Hippel-Lindau (VHL) tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation.
Western blot analyses using two distinct antibodies against unique regions of this protein confirm consistent molecular weight detection.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.