Thermo Fisher Scientific PKC theta Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive control: Jurkat
• Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (80%), Rhesus Monkey (99%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Protein Kinase C (PKC) isoforms are serine/threonine kinases involved in signal transduction pathways governing differentiation, proliferation, gene expression, brain function, membrane transport, and cytoskeletal organization. PKC acts as a key regulator of cell cycle transitions (G1 and G2 checkpoints), with effects depending on activation timing and isozyme type.
At least 12 PKC isoforms have been identified in humans, including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. PKC beta II is expressed in cardiac muscle, intestinal epithelium, kidney, and pancreas, and is associated with cell cycle progression and cancer proliferation.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.