Thermo Fisher Scientific TRAF3 Polyclonal Antibody
TRAF3 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 시료에 반응하며 WB 및 ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며 1 mg/mL 농도. 연구용으로만 사용.
- 카탈로그번호
- PA529091
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRAF3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment (amino acids 61–300 of Human TRAF3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2546567 |
Product Specific Information
- Recommended positive control: TRAF3-transfected 293T
- Predicted reactivity: Mouse (96%), Rat (84%), Bovine (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tumor necrosis factor (TNF)-induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins such as TRAFs. TRAFs are cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g., RANK, CD30, CD40) and the interleukin-1 receptor.
The carboxy-terminal region of TRAFs enables self-association and receptor interaction following ligand-induced oligomerization. Six TRAFs (TRAF1–TRAF6) have been identified.
TRAF3, originally named CRAF1, interacts directly with the CD40 cytoplasmic tail via a region similar to TNF-alpha receptor-associated factors. TRAF3 binds only a single site containing the sequence PEQET, while TRAF1 and TRAF2 can bind to both PEQET and an additional downstream domain.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.