Thermo Fisher Scientific APBB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human APBB2. Recombinant protein control fragment (Product #RP-102098). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:APBB2,uniProtId:Q92870-1,ncbiNodeId:9606,antigenRange:132-256,antigenLength:758,antigenImageFileName:PA5-54816_APBB2_Q92870-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54816_APBB2_Q92870-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638061

Product Specific Information

Immunogen sequence: SEKLEGKEPH PQDSSSCEIL PSQPRRTKSF LNYYADLETS ARELEQNRGN HHGTAEEKSQ PVQGQASTII GNGDLLLQKP NRPQSSPEDG QVATVSSSPE TKKDHPKTGA KTDCALHRIQ NLAPS

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 23%.

Target Information

The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2. This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer`s disease. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.