Thermo Fisher Scientific APBB2 Polyclonal Antibody
Thermo Fisher Scientific의 APBB2 폴리클로날 항체는 인간 단백질에 반응하며 Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, 0.2 mg/mL 농도의 액상 형태로 제공됩니다. Alzheimer 연구 등 신호전달 관련 단백질 분석에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human APBB2. Recombinant protein control fragment (Product # RP-102098) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638061 |
Product Specific Information
Immunogen sequence:
SEKLEGKEPH PQDSSSCEIL PSQPRRTKSF LNYYADLETS ARELEQNRGN HHGTAEEKSQ PVQGQASTII GNGDLLLQKP NRPQSSPEDG QVATVSSSPE TKKDHPKTGA KTDCALHRIQ NLAPS
Sequence identity:
- Mouse: 85%
- Rat: 23%
Target Information
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2.
This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction.
Polymorphisms in this gene have been associated with Alzheimer’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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