Thermo Fisher Scientific DUOX1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DUOX1. Recombinant protein control fragment (Product #RP-91278).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640822

Product Specific Information

Immunogen sequence: QHKEELTWED FHFMLRDHNS ELRFTQLCVK GVEVPEVIKD LCRRASYISQ DMICPSPRVS ARCSRSDIET ELTPQRLQCP MDTDPPQEIR RRFGKKVTSF QP

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.

Target Information

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.