Thermo Fisher Scientific SON Polyclonal Antibody
Thermo Fisher Scientific의 SON Polyclonal Antibody는 인간 SON 단백질을 인식하는 토끼 다클론 항체입니다. IHC(P) 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA554814
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SON. Recombinant protein control fragment (Product # RP-91770) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647743 |
Product Specific Information
Immunogen sequence:
TEVAIESTPM ILESSIMSSH VMKGINLSSG DQNLAPEIGM QEIALHSGEE PHAEEHLKGD FYESEHGINI DLNINNHLIA KEMEHNTVCA AGTSPVGEIG EEKILPTSET KQRTVLDTYP GVSEADAGET LSSTGP
Highest antigen sequence identity to the following orthologs:
- Mouse: 59%
- Rat: 60%
Target Information
The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined.
[Provided by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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