
Thermo Fisher Scientific Factor X/Xa Polyclonal Antibody
Thermo Fisher Scientific의 Factor X/Xa 폴리클로날 항체는 인간 Factor X를 인식하며 Western blot 및 ELISA에 적합합니다. Sheep IgG 기반 비결합형 항체로 높은 농도(11 mg/mL)를 제공하며, 연구용으로만 사용됩니다. 혈액응고 관련 단백질 연구에 유용합니다.
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Thermo Fisher Scientific Factor X/Xa Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human Factor X |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 11 mg/mL |
| Purification | SDS-PAGE |
| Storage buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074345 |
Product Specific Information
PA1-43047 detects Factor X in human samples.
PA1-43047 has been successfully used in Western blot and ELISA applications.
PA1-43047 was derived from human Factor X.
Target Information
Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by excision of the tripeptide RKR.
Two chains are held together by one or more disulfide bonds:
- The light chain contains two EGF-like domains.
- The heavy chain contains the catalytic domain, homologous to other hemostatic serine proteases.
The mature factor is activated by cleavage of the activation peptide by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway).
Activated Factor X converts prothrombin to thrombin in the presence of factor Va, Ca²⁺, and phospholipid during blood clotting.
Mutations of this gene can result in Factor X deficiency, a hemorrhagic condition of variable severity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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