Thermo Fisher Scientific Factor VII Polyclonal Antibody
Human Factor VII를 인식하는 Sheep Polyclonal Antibody로, Western Blot 및 ELISA에 적합. 고농도(9.1 mg/mL) 액상 형태로 제공되며, SDS-PAGE로 정제됨. -20°C 보관, 연구용 전용 시약.
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- PA143043
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Thermo Fisher Scientific Factor VII Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human factor VII |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 9.1 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074330 |
Product Specific Information
PA1-43043 detects Factor VII in human samples.
It has been successfully used in Western blot and ELISA applications.
Derived from human factor VII.
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis.
It circulates in the blood in a zymogen form and is converted to an active form by minor proteolysis mediated by factor IXa, Xa, XIIa, or thrombin.
Upon activation, a heavy chain (catalytic domain) and a light chain (two EGF-like domains) are generated and held together by a disulfide bond.
In the presence of factor III and calcium ions, activated factor VII further activates the coagulation cascade by converting factor IX to IXa and/or factor X to Xa.
Defects in F7 production can cause coagulopathy.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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