Thermo Fisher Scientific C-Myc Polyclonal Antibody, FITC
FITC 형광 표지된 Thermo Fisher Scientific C-Myc Polyclonal Antibody는 Western blot, ELISA, Immunoprecipitation에 적합합니다. 인간 및 고양이 등 다양한 종에 반응하며, 세포 증식 및 종양 연구용으로 사용됩니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–454 on human cMyc protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The c-Myc protein is a 62 kDa transcription factor encoded by the c-Myc gene on human chromosome 8q24. It is commonly activated in various tumor cells and plays a key role in cellular proliferation, differentiation, apoptosis, and cell cycle progression.
Phosphorylation at Thr58/Ser62 by kinases such as GSK3, CDK, ERK2, and JNK is associated with cell proliferation and regulation.
c-Myc is essential for vasculogenesis and angiogenesis in tumor development. Deregulated expression can induce apoptosis and contribute to neoplastic diseases.
Amplification or translocation of the c-Myc gene is observed in multiple human tumors, including lung, breast, colon, and Burkitt’s lymphoma.
Antibodies against c-Myc epitopes recognize Myc-tagged fusion proteins at either amino- or carboxy-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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