Thermo Fisher Scientific H4ac pan-acetyl (K5,K8,K12,K16) Polyclonal Antibody
Histone H4의 다중 아세틸화(K5, K8, K12, K16)를 인식하는 Rabbit Polyclonal Antibody. ICC, ELISA, ChIP, Peptide Array에 사용 가능. Antigen affinity chromatography로 정제되었으며 PBS buffer에 보관. 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:250 |
| ELISA | 1:1,000 |
| ChIP assay | - |
| Peptide Array | 1:20,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to the human histone H4 region containing acetylated lysines 5, 8, 12, and 16 (H4K5,8,12,16ac) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.05% sodium azide, 0.05% ProClin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608362 |
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction.
The histone H4 gene is intronless, encodes a member of the histone H4 family, and is located in the large histone gene cluster on chromosome 6. Transcripts from this gene lack polyA tails but contain a palindromic termination element.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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