Thermo Fisher Scientific Phospho-RUNX1 (Ser397) Polyclonal Antibody
RUNX1 단백질의 Ser397 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 인간, 마우스, 랫트 반응성. 고순도 액상 형태로 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RUNX1 (Accession Q01196), corresponding to amino acid residues around phosphorylated Ser397 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817037 |
Product Specific Information
Antibody detects endogenous levels of RUNX1 / AML1 only when phosphorylated at Ser397.
Target Information
RUNX1 belongs to the mammalian RUNX family of DNA binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac and placenta. It is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow, and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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