
Thermo Fisher Scientific ACVR2B Polyclonal Antibody
Rabbit에서 유래한 ACVR2B 폴리클로날 항체로, 인간 ACVR2B 재조합 단백질을 면역원으로 사용. 비결합형 액상 형태이며 0.05 mg/mL 농도. TGF-beta 신호 경로 연구에 적합. 단기 4°C, 장기 -20°C 보관 권장.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ACVR2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789457 |
Product Specific Information
Immunogen sequence:
TPGMKHENLL QFIAAEKRGS NLEVELWLIT AFHDKGSLTD YLKGNIITWN ELCHVAETMS RGLSYLHEDV PWCRGEGHKP SIAHRDFKSK NVLLKSDLTA V
Target Information
ACVR2B is a type II member of the TGF-beta family of receptor serine/threonine kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of seven of the nine cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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