Thermo Fisher Scientific ACVR2B Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ACVR2B

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789457

Product Specific Information

Immunogen sequence: TPGMKHENLL QFIAAEKRGS NLEVELWLIT AFHDKGSLTD YLKGNIITWN ELCHVAETMS RGLSYLHEDV PWCRGEGHKP SIAHRDFKSK NVLLKSDLTA V

Target Information

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.