Thermo Fisher Scientific NQO1 Polyclonal Antibody
Thermo Fisher Scientific의 NQO1 Polyclonal Antibody는 인간 NQO1 단백질을 인식하는 토끼 IgG 기반 항체입니다. Western blot, IHC, ICC/IF 실험에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NQO1. Recombinant protein control fragment (Product #RP-88713) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789453 |
Product Specific Information
Immunogen sequence:
FRSKKAVLSI TTGGSGSMYS LQGIHGDMNV ILWPIQSGIL HFCGFQVLEP QLTYSIGHTP ADARIQILEG WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG HHLGKSIPTD NQIKAR
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1’s enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been observed in many tumors and is also associated with Alzheimer’s disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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