Thermo Fisher Scientific Phospho-ATF4 (Ser245) Polyclonal Antibody
ATF4 단백질의 Ser245 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도(>95%) 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publications |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human ATF4 around the phosphorylation site of Serine 245 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553621 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 42 kDa.
Purity is >95% by SDS-PAGE.
Target Information
This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein capable of binding a tax-responsive enhancer element in the LTR of HTLV-1. It was also characterized as cAMP-response element binding protein 2 (CREB-2).
The encoded protein belongs to a family of DNA-binding proteins that includes the AP-1 family, CREBs, and CREB-like proteins. These transcription factors share a leucine zipper region involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids functioning as a DNA-binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-36624_ATF4_P18848-1_Rabbit.svg, PA5-36624_ATF4_P18848-1_Rabbit_PDP.jpeg)
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