Thermo Fisher Scientific PGES2 Polyclonal Antibody
PGES2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트에 반응. IHC, ICC, Flow, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제 및 안정적 액상 형태로 연구용에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse PGE2, amino acids 281–384 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PTGES2 gene encodes the enzyme prostaglandin E synthase 2 (PTGES2), crucial for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme functions downstream of the cyclooxygenase (COX) pathway, interacting with COX-1 and COX-2. PTGES2 regulates PGE2 levels, influencing inflammation, fever, pain, immune responses, and vascular functions. It is a membrane-associated protein with distinct regulatory properties compared to other prostaglandin synthases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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