Thermo Fisher Scientific GNAI3 Recombinant Rabbit Monoclonal Antibody (HL2096)
GNAI3 단백질을 표적으로 하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot 및 IHC(Paraffin)에서 사용 가능. HEK293 세포 발현, Protein A 정제, PBS 버퍼에 1 mg/mL 농도. Human, Mouse, Rat 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2096 |
| Immunogen | Recombinant fragment of human GNAI3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094280 |
Target Information
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each receptor detects an extracellular stimulus (such as a photon, pheromone, odorant, hormone, or neurotransmitter), while effectors like adenyl cyclase generate intracellular messengers.
In mammals, G protein alpha, beta, and gamma polypeptides are encoded by at least 16, 4, and 7 genes, respectively. The alpha subunits bind and hydrolyze GTP and regulate effector activity. Four distinct classes of Galpha subunits have been identified: Gs, Gi, Gq, and Galpha 12/13.
The Gi class includes all alpha subunits susceptible to pertussis toxin modifications, such as Galpha i-1, Galpha i-2, Galpha i-3, Galpha o, Galpha t1, Galpha t2, Galpha z, and Galpha gust. Of these, the three Galpha i subtypes function to open atrial potassium channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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