Thermo Fisher Scientific Phospho-FGFR1 (Tyr766) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated FGFR1 (Tyr766). Western blot 및 IHC(P)에서 사용 가능. 고순도 액상 형태로 제공되며, -20°C 보관. 세포 성장 및 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr766 (Q-E-YP-L-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554872 |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family, which includes four membrane-spanning tyrosine kinases (FGFR1–4) serving as high-affinity receptors for 17 growth factors (FGF1–17).
The FGF Receptor family plays an important role in various biological processes such as mesoderm induction, cell growth and migration, organ formation, and bone growth.
FGFR1 undergoes alternative splicing, generating multiple variants expressed during embryonic development and in adults.
Mutations or aberrations in FGFR1 are linked to diseases including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, non-syndromic trigonocephaly, Jackson-Weiss syndrome, and Antley-Bixler syndrome.
Chromosomal aberrations involving FGFR1 are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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