
Thermo Fisher Scientific Granzyme A Monoclonal Antibody (356412)
인간 Granzyme A를 특이적으로 인식하는 Mouse IgG2b 단일클론 항체. ICC/IF, Flow Cytometry, IP 등 다양한 응용에 적합. 단백질 A/G 정제, 무보존제 PBS 버퍼, 동결건조 형태로 제공. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 356412 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Granzyme A (Cys26–Val262) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609469 |
Product Specific Information
- In direct ELISAs, no cross-reactivity with recombinant human Granzyme B, C, D, G, or H is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They protect the host by lysing cells bearing nonself antigens, typically peptides or proteins from intracellular pathogens.
Granzyme A is a T cell- and NK cell-specific serine protease that may function as a common component necessary for target cell lysis by CTL and NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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