Thermo Fisher Scientific FAM3A Monoclonal Antibody (358112)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

358112

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FAM3A Phe34-Ser230 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM3A,uniProtId:P98173-1,ncbiNodeId:9606,antigenRange:34-230,antigenLength:230,antigenImageFileName:MA5-24107_FAM3A_P98173-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24107_FAM3A_P98173-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608211

Product Specific Information

In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse FAM3A is observed and no cross-reactivity with recombinant human (rh) FAM3B, rhFAM3C, or rhFAM3D is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

A novel cytokine-like gene family using structure-based methods to search for novel four-helix-bundle cytokines in genomics databases. There are four genes in this family, FAM3A, FAM3B, FAM3C, and FAM3D, each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence. Northern analysis indicates that FAM3B is highly expressed in pancreas, FAM3D in placenta, and FAM3A and FAM3C in almost all tissues. Immunohistochemistry showed that FAM3A is expressed prominently in the vascular endothelium, particularly capillaries. Fam3a staining in capillary endothelium and endocardium of heart, as well as vascular endothelial staining in many other tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.