Thermo Fisher Scientific Phospho-TGF beta Receptor II (Ser225) Polyclonal Antibody
TGF beta Receptor II의 Ser225 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 액상 형태, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthesized phosphopeptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transforming Growth Factor, beta receptor 2 (TGFBR2; also known as AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It plays a key role in regulating cell proliferation.
TGFBR2 encodes the gamma subunit of the catalytic core of mitochondrial ATP synthase, which catalyzes ATP synthesis using a proton gradient across the inner membrane during oxidative phosphorylation. The enzyme complex consists of two main components: the soluble catalytic core (F1) and the membrane-spanning proton channel (Fo). The F1 portion includes five subunits (alpha, beta, gamma, delta, epsilon) with a stoichiometry of 3 alpha, 3 beta, and one each of the others. The Fo portion includes subunits a, b, and c.
Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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