Thermo Fisher Scientific KCNT1 Polyclonal Antibody
KCNT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 고순도의 Protein A 정제 항체입니다. 인간 KCNT1(aa 101-200) 유래 펩타이드로 면역화되어 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human KCNT1 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Potassium channels are a complex class of voltage-gated ion channels involved in diverse physiological functions such as neurotransmitter release, heart rate regulation, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume control.
The KCNT1 gene encodes a sodium-activated potassium channel subunit that participates in ion conductance and developmental signaling pathways. Mutations in KCNT1 are associated with early-onset epileptic disorders, including malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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