Thermo Fisher Scientific PDE8B Polyclonal Antibody, FITC
PDE8B 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제 및 형광 검출용으로 최적화. -20°C 어두운 곳에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic cyclic peptide common to all PDE8B variants |
| Conjugate | FITC |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5′,3′-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5′-monophosphates. Mammalian PDEs are grouped into several families based on substrate affinities, inhibitor sensitivities, regulatory modes, and amino acid sequence homologies. The PDE8 family includes high-affinity, cAMP-specific, IBMX-insensitive PDEs such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that contributes to their unique regulatory properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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