Thermo Fisher Scientific CYP24A1 Monoclonal Antibody (1E1)
CYP24A1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(1E1). Western blot 및 ELISA에 사용 가능하며, 인간 시료에 반응. PBS buffer 기반 액상 형태, 보존제 무첨가. -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA (ELISA) | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E1 |
| Immunogen | CYP24A1 (NP_000773, 415 a.a. ~ 514 a.a.) partial recombinant protein with GST tag. MW of GST tag alone: 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LMLNTQVLGS SEDNFEDSSQ FRPERWLQEK EKINPFAHLP FGVGKRMCIG RRLAELQLHL ALCWIVRKYD IQATDNEPVE MLHSGTLVPS RELPIAFCQR
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain.
By regulating vitamin D3 levels, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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